HPV-specific binding molecules

Provided are binding molecules, such as TCRs or antigen binding fragments thereof and antibodies and antigen-binding fragments thereof, such as those that recognize or bind human papilloma virus (HPV) 16, including HPV 16 E6 and HPV 16 E7. Also provided are engineered cells containing such binding m...

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Main Authors Koppstein, David, Goldfless, Stephen, Johnstone, Timothy, Sather, Blythe, Timberlake, Sonia, Jiang, Yue, Toy, Dean Y, Sissons, James, Belmont, Brian, Nguyen, Hieu, Ebens, Allen, Peper, Haley, Croft, Alexandra, Brandt, Cameron
Format Patent
LanguageEnglish
Published 31.08.2023
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Abstract Provided are binding molecules, such as TCRs or antigen binding fragments thereof and antibodies and antigen-binding fragments thereof, such as those that recognize or bind human papilloma virus (HPV) 16, including HPV 16 E6 and HPV 16 E7. Also provided are engineered cells containing such binding molecules, compositions containing the binding molecules or engineered cells, and methods of treatment, such as administration of the binding molecules, engineered cells, or compositions.
AbstractList Provided are binding molecules, such as TCRs or antigen binding fragments thereof and antibodies and antigen-binding fragments thereof, such as those that recognize or bind human papilloma virus (HPV) 16, including HPV 16 E6 and HPV 16 E7. Also provided are engineered cells containing such binding molecules, compositions containing the binding molecules or engineered cells, and methods of treatment, such as administration of the binding molecules, engineered cells, or compositions.
Author Ebens, Allen
Toy, Dean Y
Croft, Alexandra
Goldfless, Stephen
Nguyen, Hieu
Sather, Blythe
Jiang, Yue
Timberlake, Sonia
Koppstein, David
Sissons, James
Brandt, Cameron
Johnstone, Timothy
Peper, Haley
Belmont, Brian
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– fullname: Sather, Blythe
– fullname: Timberlake, Sonia
– fullname: Jiang, Yue
– fullname: Toy, Dean Y
– fullname: Sissons, James
– fullname: Belmont, Brian
– fullname: Nguyen, Hieu
– fullname: Ebens, Allen
– fullname: Peper, Haley
– fullname: Croft, Alexandra
– fullname: Brandt, Cameron
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Snippet Provided are binding molecules, such as TCRs or antigen binding fragments thereof and antibodies and antigen-binding fragments thereof, such as those that...
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SubjectTerms CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
Title HPV-specific binding molecules
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