Pharmaceutical formulations for sustained release of sebacoyl dinalbuphine ester
The present invention relates to injectable, extended-release, pharmaceutical formulations comprising a nalbuphine ester prodrug homogenously dissolved in a solution comprising a pharmaceutically acceptable oil and an oil-miscible retaining solvent, as well as manufacturing processes and medical use...
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| Main Authors | , , , , , |
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| Format | Patent |
| Language | English |
| Published |
08.04.2021
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The present invention relates to injectable, extended-release, pharmaceutical formulations comprising a nalbuphine ester prodrug homogenously dissolved in a solution comprising a pharmaceutically acceptable oil and an oil-miscible retaining solvent, as well as manufacturing processes and medical uses of the formulations. The invention further provides methods for adjusting the duration of action of the formulations by varying the ratio of the pharmaceutically acceptable oil and the oil-miscible retaining solvent. |
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| AbstractList | The present invention relates to injectable, extended-release, pharmaceutical formulations comprising a nalbuphine ester prodrug homogenously dissolved in a solution comprising a pharmaceutically acceptable oil and an oil-miscible retaining solvent, as well as manufacturing processes and medical uses of the formulations. The invention further provides methods for adjusting the duration of action of the formulations by varying the ratio of the pharmaceutically acceptable oil and the oil-miscible retaining solvent. |
| Author | Tsai Jr., Shin Chou, david chih-Kuang Tien, Yu-En Huang, Jin-Ding Li, Chan-Jung Kuo, Shu-Wen |
| Author_xml | – fullname: Kuo, Shu-Wen – fullname: Tsai Jr., Shin – fullname: Li, Chan-Jung – fullname: Tien, Yu-En – fullname: Huang, Jin-Ding – fullname: Chou, david chih-Kuang |
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| RelatedCompanies | LUMOSA THERAPEUTICS CO., LTD SHANGHAI LUMOSA THERAPEUTICS CO., LTD |
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| Snippet | The present invention relates to injectable, extended-release, pharmaceutical formulations comprising a nalbuphine ester prodrug homogenously dissolved in a... |
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| Title | Pharmaceutical formulations for sustained release of sebacoyl dinalbuphine ester |
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