Radiolabelled mGluR2 PET ligands
The present invention relates to novel, selective, radiolabelled mGluR2 ligands which are useful for imaging and quantifying the metabotropic glutamate receptor mGluR2 in tissues, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to p...
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Format | Patent |
Language | English |
Published |
04.03.2021
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Abstract | The present invention relates to novel, selective, radiolabelled mGluR2 ligands which are useful for imaging and quantifying the metabotropic glutamate receptor mGluR2 in tissues, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue, cells or a mammal, in vitro or in vivo and to precursors of said compounds. |
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AbstractList | The present invention relates to novel, selective, radiolabelled mGluR2 ligands which are useful for imaging and quantifying the metabotropic glutamate receptor mGluR2 in tissues, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue, cells or a mammal, in vitro or in vivo and to precursors of said compounds. |
Author | Van Gool, Michiel Luc Maria Alcazar-Vaca, Manuel Jesus Bormans, Guy Maurits R Andres-Gil, Jose Ignacio Celen, Sofie Jeanne Leopoldine Verbeek, Joost |
Author_xml | – fullname: Alcazar-Vaca, Manuel Jesus – fullname: Verbeek, Joost – fullname: Celen, Sofie Jeanne Leopoldine – fullname: Van Gool, Michiel Luc Maria – fullname: Bormans, Guy Maurits R – fullname: Andres-Gil, Jose Ignacio |
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Snippet | The present invention relates to novel, selective, radiolabelled mGluR2 ligands which are useful for imaging and quantifying the metabotropic glutamate... |
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Title | Radiolabelled mGluR2 PET ligands |
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