Aminopyridyloxypyrazole compounds

The present invention relates to novel aminopyridyloxypyrazole compounds that inhibit the activity of transforming growth factor beta receptor 1 (TGFpRI), pharmaceutical compositions comprising the compounds, and methods of using the compounds to treat cancer, preferably colon cancer, melanoma, hepa...

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Bibliographic Details
Main Authors Sawyer, Jason Scott, Zhao, Gaiying, Beight, Douglas W, Joseph, Sajan, Parthasarathy, Saravanan, Coates, David A, Pei, Huaxing, McMillen, William T, Wolfangel, Craig D
Format Patent
LanguageEnglish
Published 15.11.2018
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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