Cis-morpholinone and other compounds as MDM2 inhibitors for the treatment of cancer
The present invention provides MDM2 inhibitor compounds of Formula (I), or the pharmaceutically acceptable salts thereof, wherein the variables are defined above, which compounds are useful as therapeutic agents, particularly for the treatment of cancers. The present invention also relates to pharma...
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| Main Authors | , , , , , , , , , , , , |
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| Format | Patent |
| Language | English |
| Published |
06.09.2018
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The present invention provides MDM2 inhibitor compounds of Formula (I), or the pharmaceutically acceptable salts thereof, wherein the variables are defined above, which compounds are useful as therapeutic agents, particularly for the treatment of cancers. The present invention also relates to pharmaceutical compositions that contain an MDM2 inhibitor. |
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| AbstractList | The present invention provides MDM2 inhibitor compounds of Formula (I), or the pharmaceutically acceptable salts thereof, wherein the variables are defined above, which compounds are useful as therapeutic agents, particularly for the treatment of cancers. The present invention also relates to pharmaceutical compositions that contain an MDM2 inhibitor. |
| Author | Sun, Daqing Yan, Xuelei Beck, Hilary Plake Degraffenreid, Michael R Medina, Julio C Gonzalez Lopez De Turiso, Felix Kayser, Frank Bartberger, Michael D Julian, Lisa D Rew, Yosup Fox, Brian M Olson, Steven H Roveto, Philip M |
| Author_xml | – fullname: Yan, Xuelei – fullname: Beck, Hilary Plake – fullname: Olson, Steven H – fullname: Fox, Brian M – fullname: Julian, Lisa D – fullname: Degraffenreid, Michael R – fullname: Roveto, Philip M – fullname: Bartberger, Michael D – fullname: Sun, Daqing – fullname: Gonzalez Lopez De Turiso, Felix – fullname: Medina, Julio C – fullname: Rew, Yosup – fullname: Kayser, Frank |
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| Snippet | The present invention provides MDM2 inhibitor compounds of Formula (I), or the pharmaceutically acceptable salts thereof, wherein the variables are defined... |
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| Title | Cis-morpholinone and other compounds as MDM2 inhibitors for the treatment of cancer |
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