Combinations of a GLP1R agonist and metformin and use thereof for the treatment of type 2 diabetes and other disorders

• Main Authors: Clark, Bradley Alan, Quada Jr., James C, Yokum, Thomas Scott, Mjalli, Adnan M. M, Andrews, Robert Carl, Polisetti, Dharma Rao, Valcarce Lopez, Maria Carmen, Davis, Stephen Thomas
• Format: Patent
• Language: English
• Published: 11.10.2018
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention provides uses of a glucagon-like peptide 1 receptor agonist in combination with metformin. Uses include treating type 2 diabetes, lowering blood glucose, and improving the therapeutic effectiveness of metformin. The invention also provides pharmaceutical compositions that compr...