Combinations of a GLP1R agonist and metformin and use thereof for the treatment of type 2 diabetes and other disorders

The present invention provides uses of a glucagon-like peptide 1 receptor agonist in combination with metformin. Uses include treating type 2 diabetes, lowering blood glucose, and improving the therapeutic effectiveness of metformin. The invention also provides pharmaceutical compositions that compr...

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Main Authors Clark, Bradley Alan, Quada Jr., James C, Yokum, Thomas Scott, Mjalli, Adnan M. M, Andrews, Robert Carl, Polisetti, Dharma Rao, Valcarce Lopez, Maria Carmen, Davis, Stephen Thomas
Format Patent
LanguageEnglish
Published 11.10.2018
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract The present invention provides uses of a glucagon-like peptide 1 receptor agonist in combination with metformin. Uses include treating type 2 diabetes, lowering blood glucose, and improving the therapeutic effectiveness of metformin. The invention also provides pharmaceutical compositions that comprise a GLP1R agonist and metformin.
AbstractList The present invention provides uses of a glucagon-like peptide 1 receptor agonist in combination with metformin. Uses include treating type 2 diabetes, lowering blood glucose, and improving the therapeutic effectiveness of metformin. The invention also provides pharmaceutical compositions that comprise a GLP1R agonist and metformin.
Author Valcarce Lopez, Maria Carmen
Polisetti, Dharma Rao
Davis, Stephen Thomas
Mjalli, Adnan M. M
Quada Jr., James C
Clark, Bradley Alan
Andrews, Robert Carl
Yokum, Thomas Scott
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– fullname: Andrews, Robert Carl
– fullname: Polisetti, Dharma Rao
– fullname: Valcarce Lopez, Maria Carmen
– fullname: Davis, Stephen Thomas
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Snippet The present invention provides uses of a glucagon-like peptide 1 receptor agonist in combination with metformin. Uses include treating type 2 diabetes,...
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SubjectTerms HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title Combinations of a GLP1R agonist and metformin and use thereof for the treatment of type 2 diabetes and other disorders
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