Epsilon toxin epitopes from clostridium perfringens with reduced toxicity

• Main Authors: TITBALL, RICHARD W, NAYLOR, CLAIRE, BOKORI-BROWN, MONIKA
• Format: Patent
• Language: English
• Published: 16.10.2014
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

There is provided an epsilon toxin epitope polypeptide comprising a sequence of at least 10 contiguous amino acids from SEQ ID NO:3, the sequence comprising a mutation of at least one tyrosine residue compared to the equivalent sequence in SEQ ID NO:3, the polypeptide being capable of binding an ant...