TDP-43 specific binding molecules

Provided are novel TDP-43 -specific binding molecules including polypeptides such as human antibodies, as well as fragments, derivatives and variants thereof. Also provided are methods related to these TDP-43 specific binding molecules. Assays, f4 kits, and solid supports related to TDP-43 -specific...

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Main Authors Hock, Christoph, Grimm, Jan, Barenco Monstrasio, Maria Grazia, Coomaraswamy, Janaky, Nitsch, Roger, Quintero-Monzon, Omar, Weinreb, Paul, Montrasio, Fabio, Baeriswyl, Jean-Luc
Format Patent
LanguageEnglish
Published 10.03.2016
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Provided are novel TDP-43 -specific binding molecules including polypeptides such as human antibodies, as well as fragments, derivatives and variants thereof. Also provided are methods related to these TDP-43 specific binding molecules. Assays, f4 kits, and solid supports related to TDP-43 -specific binding molecules, including polypeptides such as, human antibodies are also disclosed. The TDP-43-specific binding molecule, antibody, immunoglobulin chain(s), as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for TDP-43 targeted immunotherapy and diagnosis, re spectively.
Bibliography:Application Number: AU20120327211