Substituted bicyclic aza-heterocycles and analogues as sirtuin modulators

• Main Authors: SPRINGER, STEPHANIE K, BLUM, CHARLES A, DISCH, JEREMY S
• Format: Patent
• Language: English
• Published: 01.05.2014
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY

Provided herein are novel substituted bicyclic aza-heterocycle sirtuin- modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example,...