Heterocyclic inhibitors of MEK and methods of use thereof

Disclosed are MEK inhibitors useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals, and inflammatory conditions. Also disclosed are methods of using such compounds in the treatment of hyperproliferative diseases in mammals and pharmaceutical compositions...

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Main Authors LYSSIKATOS, JOSEPH P, BOOTH, REBECCA JANE, MARLOW, ALLISON L, SEO, JEONGBEOB, PITTAM, JOHN DAVID, BLAKE, JIM, LEONARD, JOHN, FIELDING, MARK RICHARD, WALLACE, ELI, STOREY, RICHARD ANTHONY, YANG, HONG WOON
Format Patent
LanguageEnglish
Published 30.08.2012
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Abstract Disclosed are MEK inhibitors useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals, and inflammatory conditions. Also disclosed are methods of using such compounds in the treatment of hyperproliferative diseases in mammals and pharmaceutical compositions containing such compounds.
AbstractList Disclosed are MEK inhibitors useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals, and inflammatory conditions. Also disclosed are methods of using such compounds in the treatment of hyperproliferative diseases in mammals and pharmaceutical compositions containing such compounds.
Author BLAKE, JIM
STOREY, RICHARD ANTHONY
BOOTH, REBECCA JANE
WALLACE, ELI
LEONARD, JOHN
YANG, HONG WOON
FIELDING, MARK RICHARD
MARLOW, ALLISON L
LYSSIKATOS, JOSEPH P
SEO, JEONGBEOB
PITTAM, JOHN DAVID
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– fullname: BLAKE, JIM
– fullname: LEONARD, JOHN
– fullname: FIELDING, MARK RICHARD
– fullname: WALLACE, ELI
– fullname: STOREY, RICHARD ANTHONY
– fullname: YANG, HONG WOON
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Snippet Disclosed are MEK inhibitors useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals, and inflammatory conditions....
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Title Heterocyclic inhibitors of MEK and methods of use thereof
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