Substituted 3-cyanoquinolines as protein tyrosine kinases inhibitors

C:NRPnbhDCORXS\4502194_1 DOC-30/07/2012 The present invention provides substituted 3-cyanoquinolines as protein tyrosine kinases inhibitors and pharmaceutical compositions containing those compounds which can be used in methods of treating, inhibiting the growth of or eradicating a neoplasm in a mam...

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Main Authors ZHANG, NAN, FLOYD JR., MIDDLETON BRAWNER FLOYD, TSOU, HWEI-RU, WISSNER, ALLAN, HAMANN, PHILIP ROSS, BERGER, DAN MAARTEN, FROST, PHILIP
Format Patent
LanguageEnglish
Published 23.08.2012
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Abstract C:NRPnbhDCORXS\4502194_1 DOC-30/07/2012 The present invention provides substituted 3-cyanoquinolines as protein tyrosine kinases inhibitors and pharmaceutical compositions containing those compounds which can be used in methods of treating, inhibiting the growth of or eradicating a neoplasm in a mammal. The compounds and pharmaceutical compositions containing them may also be used on methods of treating, inhibiting the progression of or eradicating polycystic kidney disease in a mammal. The present invention also provides a process for preparing the compounds of this invention.
AbstractList C:NRPnbhDCORXS\4502194_1 DOC-30/07/2012 The present invention provides substituted 3-cyanoquinolines as protein tyrosine kinases inhibitors and pharmaceutical compositions containing those compounds which can be used in methods of treating, inhibiting the growth of or eradicating a neoplasm in a mammal. The compounds and pharmaceutical compositions containing them may also be used on methods of treating, inhibiting the progression of or eradicating polycystic kidney disease in a mammal. The present invention also provides a process for preparing the compounds of this invention.
Author WISSNER, ALLAN
FROST, PHILIP
HAMANN, PHILIP ROSS
FLOYD JR., MIDDLETON BRAWNER FLOYD
ZHANG, NAN
TSOU, HWEI-RU
BERGER, DAN MAARTEN
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– fullname: HAMANN, PHILIP ROSS
– fullname: BERGER, DAN MAARTEN
– fullname: FROST, PHILIP
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Snippet C:NRPnbhDCORXS\4502194_1 DOC-30/07/2012 The present invention provides substituted 3-cyanoquinolines as protein tyrosine kinases inhibitors and pharmaceutical...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Title Substituted 3-cyanoquinolines as protein tyrosine kinases inhibitors
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