Imidazo-pyridine derivatives as activin-like receptor kinase (ALK4 or ALK5) inhibitors

• Main Authors: NIKOLAUS JOHANNES STIEFL, CATHERINE LEBLANC, DUNCAN SHAW, CATHY RITCHIE
• Format: Patent
• Language: English
• Published: 05.11.2009
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

Compounds of formula (I): in free or salt or solvate form, where X, R1, R2, R3 and R4 have the meanings as indicated in the specification, are useful for treating diseases mediated by the ALK-5 and/or ALK-4 receptor. Pharmaceutical compositions that contain the compounds and processes for preparing...