Aryl sulfamide derivatives and methods of their use

The present invention is directed to aryl sulfamide derivatives of formula I: or a pharmaceutically acceptable salt, stereoisomer or tautomer thereof, which are monoamine reuptake inhibitors, compositions containing these derivatives, and methods of their use for the prevention and treatment of cond...

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Main Authors CASEY CAMERON MC COMAS, JOEL ADAM GOLDBERG, PUWEN ZHANG, JOSEPH P. SABATUCCI, PAIGE ERIN MAHANEY, EUGENE ANTHONY TEREFENKO, CHARLES WILLIAM MANN, ANDREW FENSOME, DOUGLAS JOHN JENKINS, RICHARD PAGE WOODWORTH JR, EUGENE JOHN TRYBULSKI, MATTHEW L. CRAWLEY, MICHAEL ANTHONY MARELLA, STEPHEN TODD COHN, AN THIEN VU, CALLAIN YOUNGHEE KIM, DAVID JOHN O'NEILL
Format Patent
LanguageEnglish
Published 19.06.2008
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Abstract The present invention is directed to aryl sulfamide derivatives of formula I: or a pharmaceutically acceptable salt, stereoisomer or tautomer thereof, which are monoamine reuptake inhibitors, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions, including, inter alia, vasomotor symptoms, sexual dysfunction, gastrointestinal disorders and genitourinary disorder, depression disorders, endogenous behavioral disorders, cognitive disorders, diabetic neuropathy, pain, and other diseases or disorders.
AbstractList The present invention is directed to aryl sulfamide derivatives of formula I: or a pharmaceutically acceptable salt, stereoisomer or tautomer thereof, which are monoamine reuptake inhibitors, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions, including, inter alia, vasomotor symptoms, sexual dysfunction, gastrointestinal disorders and genitourinary disorder, depression disorders, endogenous behavioral disorders, cognitive disorders, diabetic neuropathy, pain, and other diseases or disorders.
Author EUGENE JOHN TRYBULSKI
PUWEN ZHANG
STEPHEN TODD COHN
JOSEPH P. SABATUCCI
DAVID JOHN O'NEILL
CASEY CAMERON MC COMAS
JOEL ADAM GOLDBERG
CHARLES WILLIAM MANN
EUGENE ANTHONY TEREFENKO
AN THIEN VU
MICHAEL ANTHONY MARELLA
ANDREW FENSOME
RICHARD PAGE WOODWORTH JR
PAIGE ERIN MAHANEY
MATTHEW L. CRAWLEY
DOUGLAS JOHN JENKINS
CALLAIN YOUNGHEE KIM
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– fullname: CHARLES WILLIAM MANN
– fullname: ANDREW FENSOME
– fullname: DOUGLAS JOHN JENKINS
– fullname: RICHARD PAGE WOODWORTH JR
– fullname: EUGENE JOHN TRYBULSKI
– fullname: MATTHEW L. CRAWLEY
– fullname: MICHAEL ANTHONY MARELLA
– fullname: STEPHEN TODD COHN
– fullname: AN THIEN VU
– fullname: CALLAIN YOUNGHEE KIM
– fullname: DAVID JOHN O'NEILL
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Snippet The present invention is directed to aryl sulfamide derivatives of formula I: or a pharmaceutically acceptable salt, stereoisomer or tautomer thereof, which...
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HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Title Aryl sulfamide derivatives and methods of their use
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