Benzazole derivatives, compositions, and methods of use as Aurora kinase inhibitors

The present invention relates to compounds and methods from the treatment of cancer. The invention provides compounds that inhibit Aurora kinase, pharmaceutical compositions comprising compounds that inhibit Aurora kinase, and methods for the treatment of cancer using the compounds of the presentati...

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Main Authors ANDREWS, ROBERT C, MJALLI, ADNAN M. M, ZHU, JEFF, GOPALASWAMY, RAMESH, GUO, XIAOCHUAN, ARIMILLI, MURTY N, SUBRAMANIAN, GOVINDAN, DAVIS, STEPHEN, GRELLA, BRIAN S
Format Patent
LanguageEnglish
Published 13.12.2012
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Abstract The present invention relates to compounds and methods from the treatment of cancer. The invention provides compounds that inhibit Aurora kinase, pharmaceutical compositions comprising compounds that inhibit Aurora kinase, and methods for the treatment of cancer using the compounds of the presentation invention or pharmaceutical compositions comprising compounds of the present invention.
AbstractList The present invention relates to compounds and methods from the treatment of cancer. The invention provides compounds that inhibit Aurora kinase, pharmaceutical compositions comprising compounds that inhibit Aurora kinase, and methods for the treatment of cancer using the compounds of the presentation invention or pharmaceutical compositions comprising compounds of the present invention.
Author ARIMILLI, MURTY N
ZHU, JEFF
ANDREWS, ROBERT C
DAVIS, STEPHEN
GRELLA, BRIAN S
GOPALASWAMY, RAMESH
GUO, XIAOCHUAN
SUBRAMANIAN, GOVINDAN
MJALLI, ADNAN M. M
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– fullname: ARIMILLI, MURTY N
– fullname: SUBRAMANIAN, GOVINDAN
– fullname: DAVIS, STEPHEN
– fullname: GRELLA, BRIAN S
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Snippet The present invention relates to compounds and methods from the treatment of cancer. The invention provides compounds that inhibit Aurora kinase,...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title Benzazole derivatives, compositions, and methods of use as Aurora kinase inhibitors
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