Glucagon receptor antagonists, preparation and therapeutic uses

• Main Authors: HIPSKIND, PHILIP ARTHUR, CHAPPELL, MARK DONALD, ZHU, GUOXIN, CONNER, SCOTT EUGENE, TRIPP, ALLIE EDWARD
• Format: Patent
• Language: English
• Published: 10.05.2012
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention discloses novel compounds of Formula (I), or pharmaceutically acceptable salts thereof, which have glucagon receptor antagonist or inverse agonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositio...