Pyrimidine amide compounds as PGDS inhibitors

This invention is directed to a compound of formula (I): wherein R, R, R and L are as defined herein, a pharmaceutical composition comprising the compound, and the use of the compound to treat allergic and/or inflammatory disorders, particularly disorders such as allergic rhinitis, asthma and/or chr...

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Main Authors MU, LAN, THURAIRATNAM, SUKANTHINI, MA, LIANG, MUNSON, HARRY RANDALL, JIANG, JOHN ZIQI, SABOL, JEFFREY STEPHEN, ALDOUS, SUZANNE C, LU, JINQI, VANDEUSEN, CHRISTOPHER LOREN
Format Patent
LanguageEnglish
Published 26.04.2012
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract This invention is directed to a compound of formula (I): wherein R, R, R and L are as defined herein, a pharmaceutical composition comprising the compound, and the use of the compound to treat allergic and/or inflammatory disorders, particularly disorders such as allergic rhinitis, asthma and/or chronic obstructive pulmonary disease (COPD).
AbstractList This invention is directed to a compound of formula (I): wherein R, R, R and L are as defined herein, a pharmaceutical composition comprising the compound, and the use of the compound to treat allergic and/or inflammatory disorders, particularly disorders such as allergic rhinitis, asthma and/or chronic obstructive pulmonary disease (COPD).
Author VANDEUSEN, CHRISTOPHER LOREN
MA, LIANG
JIANG, JOHN ZIQI
SABOL, JEFFREY STEPHEN
ALDOUS, SUZANNE C
THURAIRATNAM, SUKANTHINI
MU, LAN
LU, JINQI
MUNSON, HARRY RANDALL
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– fullname: SABOL, JEFFREY STEPHEN
– fullname: ALDOUS, SUZANNE C
– fullname: LU, JINQI
– fullname: VANDEUSEN, CHRISTOPHER LOREN
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Snippet This invention is directed to a compound of formula (I): wherein R, R, R and L are as defined herein, a pharmaceutical composition comprising the compound, and...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title Pyrimidine amide compounds as PGDS inhibitors
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