ANTI-RETROVIRAL 5,6-DISUBSTITUTED ACYCLOPYRIMIDINE NUCLEOSIDE DERIVATIVES
The present invention provides novel pyrimidine nucleoside derivatives represented by the following formula (I): HN I R2 CH (CH2)n 2,X 1 SIMILAR D3 wherein R represents e.g. an alkyl group; RZ represents e.g. a phenyl group or a 3,5-dimethylphenyl group; and R represents e.g. a vinyl group or a ethy...
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Main Authors | , , , , , , |
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Format | Patent |
Language | English |
Published |
24.07.2003
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Edition | 7 |
Subjects | |
Online Access | Get full text |
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Summary: | The present invention provides novel pyrimidine nucleoside derivatives represented by the following formula (I): HN I R2 CH (CH2)n 2,X 1 SIMILAR D3 wherein R represents e.g. an alkyl group; RZ represents e.g. a phenyl group or a 3,5-dimethylphenyl group; and R represents e.g. a vinyl group or a ethynyl group; A, B and X represent e.g. oxygene atoms; Z represents e.g. a methylene group or a carbonyl group; n is e.g. 1. The compounds were found to be highly active against wild-type and mutant HIV-1. |
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Bibliography: | Application Number: AU20030205536 |