Heterocyclic sulfonamide inhibitors of beta amyloid production

Compounds of Formula (I), wherein R1, R2, R3, R4, R5, R6, T, W, X, Y and Z are as defined herein are provided, together with pharmaceutically acceptable salt, hydrates and/or prodrugs thereof. Methods of using these compounds for inhibiting beta amyloid production and for treatment of Alzheimer'...

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Main Authors GEORGE DIAMANITIS, KEVIN, ROGER WOLLER, DEREK, CECIL COLE, DENNIS, MICHAEL KURBRAK, KRISTINA, MARTHA KUTTERER, ANTHONY, FRANK KREFT, JOSEPH, RAYMOND STOCK, DAVID, SCOTT CASEBIER, WILLIAM, JAY MOORE
Format Patent
LanguageEnglish
Published 24.05.2007
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Compounds of Formula (I), wherein R1, R2, R3, R4, R5, R6, T, W, X, Y and Z are as defined herein are provided, together with pharmaceutically acceptable salt, hydrates and/or prodrugs thereof. Methods of using these compounds for inhibiting beta amyloid production and for treatment of Alzheimer's disease and Down's syndrome are described.
Bibliography:Application Number: AU20020245123