STABILE, NICHT-HYGROSKOPISCHE, KRISTALLINE FORM VON N-ÄN-N(4-(PIPERIDIN-4-YL)BUTANOYL)-N- ETHYLGLYCYL VERBINDUNGEN

• Main Authors: LIU, ROBERT, VEMURI, NARASIMHA, WINDISCH, VINCENT, WOODWARD, RICK, MENCEL, JAMES, KUBIAK, GREGORY, VANASSE, BENOIT, CHRZAN, ZOFIA, GARDETTO, ANTHONY, SHERBINE, JAMES, TOLEDO-VELASQUEZ, DAVID, RODRIGUEZ, WALTER, POWERS, MATTHEW, SALAZAR, DIANE, SLEDESKI, ADAM
• Format: Patent
• Language: German
• Published: 15.04.2008
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention is directed to a non-hygroscopic stable crystalline form of the antithrombotic compound N-[N-[N-(4-piperdin-4-yl)butanoyl)-N-ethylglycyl]-(L)-aspartyl]-(L)- beta -cyclohexyl-alanine amide, to processes for preparing said stable crystalline form, to a pharmaceutical composition thereof,...