DISPERSIONES MOLECULARES DE DROSPIRENONA

• Main Authors: TORSTEN, WAGNER, FUNKE, ADRIAN
• Format: Patent
• Language: Spanish
• Published: 15.03.2006
• Edition: 7
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

Una composicion farmacéutica que comprende drogas esteroides, por ejemplo: progestinas y estrogenos, en forma molecularmente dispersa. Preferiblemente, las composiciones se proveen como formas solidas, semisolidas o líquidas. Dichas composiciones tiene una alta biodisponibilidad, buena estabilidad química y rápida disolucion por liberacion in vitro y se pueden producir en condiciones que no requieren equipos costosos ni recaudos de seguridad. También se describen métodos para la preparacion y uso de las composiciones. The present invention relates to pharmaceutical composition comprising steroidal drugs, such as drospirenone, in molecularly dispersed form. Preferably, the compositions are provided as solid, semi-solid or liquid forms, which in turn preferably are adapted for oral administration and preferably to be absorbed from the gastro-intestinal tract. Such compositions are found to have high bioavailability, good chemical stability, and fast in-vitro dissolution release and can be produced under conditions, which do not require costly equipment or safety guards.