Aqueous synthesis of 2-aryl-3-nitro-2Hchromenes via l-prolinamide mediated tandem oxa-Michael Henry reactions

• Published in: Journal of molecular structure Vol. 1265
• Main Authors: Rani, Dixita, Gulati, Vinny, Guleria, Mamta, Singh, Satya Prakash, Agarwal, Jyoti
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 05.10.2022
• Subjects: Chromene, Oxa-Michael Henry reaction; Heterogeneous catalysis; L-prolinamide; Water reaction; β-nitrostyrenes; Heterogeneous catalysis; L-prolinamide; Water reaction; β-nitrostyrenes; Chromene, Oxa-Michael Henry reaction

•Aqueous protocol for the synthesis of 2-aryl-3-nitro-2H-chromenes has been developed.•Simple and easily accessible l-prolinamide catalyst were used to produce the chromenes in high yields.•The efficiency of the protocol was compared in both organic and aqueous solvents.•Better efficiency was observ...