Low heritability of neopterin in the Old Order Amish

• Published in: Journal of neuroimmunology
• Main Authors: Raheja, Uttam K, Stephens, Sarah H, Fuchs, Dietmar, Pavlovich, Mary A, Mohyuddin, Hira, Yousufi, Hassaan, Ryan, Kathleen, O'Connell, Jeff, Brenner, Lisa A, Punzalan, Cecile, Lowry, Christopher A, Hoisington, Andrew J, Nijjar, Gursharon K, Groer, Maureen, Shuldiner, Alan R, Pollin, Toni I, Stiller, John W, Mitchell, Braxton D, Postolache, Teodor T
• Format: Journal Article
• Language: English
• Published: 2017
• Subjects: Allergy and Immunology; Neurology; Biomarkers; Heritability; Neopterin; Old Order Amish; Psychiatric disorders

Abstract Background Neopterin is a biomarker for cell-mediated immunity and oxidative stress, and a potential biomarker for psychiatric disorders such as depression. Heritability of immune markers is important for understanding their usefulness as potential trait versus state indicators in neuropsyc...