Cloning of the truncated Human tPA Gene in Chloroplast vector and regeneration of transplastomic tobacco plants

• Published in: Biyutiknuluzhī-i kishāvarzī Vol. 6; no. 3; pp. 149 - 166
• Main Authors: Maryam Abdoli Nasab, Mokhtar Jalali Javaran, Amin Baqi Zadeh, Houshang Alizadeh
• Format: Journal Article
• Language: Persian
• Published: Shahid Bahonar University of Kerman 01.11.2014
• Subjects: chloroplast transformation; molecular farming; tissue plasminogen activator; transplastomic

Plants are suitable replacements for current biodrugs and recombinant protein expression systems such as transgenic animals or microbial systems. As the plant plastid genome is highly polyploid, the transformation of chloroplast permits the introduction of thousands of copies of foreign gene per pla...