Three benefits of toremifene, or a trend in the current hormone therapy

Introduction of toremifene into clinical practice significantly enhances the potential of current endocrine therapy for luminal subtypes of breast cancer. Toremifene demonstrates same or greater efficacy compare with tamoxifen but has a more favorable spectrum of side effects including thromboemboli...

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Bibliographic Details
Published inMedicinskij sovet no. 8; pp. 60 - 65
Main Authors E. I. Borisova, S. L. Gutorov
Format Journal Article
LanguageRussian
Published Remedium Group LLC 01.12.2015
Subjects
breast cancer
selective estrogen receptor modulators
toremifene
рак молочной железы
селективные модуляторы рецепторов эстрогена
торемифен
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Summary:Introduction of toremifene into clinical practice significantly enhances the potential of current endocrine therapy for luminal subtypes of breast cancer. Toremifene demonstrates same or greater efficacy compare with tamoxifen but has a more favorable spectrum of side effects including thromboembolic complications. These benefits can significantly reduce the number of cases of irrational discontinuation of therapy. The possibility of safe use of high doses of toremifene including the preoperative therapy regimens which are now being studied also seems promising.
ISSN:2079-701X
2658-5790
DOI:10.21518/2079-701X-2015-8-60-65