A de novo MS1 feature detector for the Bruker timsTOF Pro

• Published in: PloS one Vol. 17; no. 11
• Main Authors: Daryl Wilding-McBride, Andrew I. Webb
• Format: Journal Article
• Language: English
• Published: Public Library of Science (PLoS) 01.01.2022

Identification of peptides by analysis of data acquired by the two established methods for bottom-up proteomics, DDA and DIA, relies heavily on the fragment spectra. In DDA, peptide features detected in mass spectrometry data are identified by matching their fragment spectra with a peptide database....