Development of a Temperature Senor Based on 19F-labeled Phosphorylated Ubiquitin

• Published in: Bopuxue zazhi Vol. 38; no. 2; pp. 173 - 181
• Main Authors: Zhi-wu ZHANG, Ju YANG, Ze-feng NIE, Shang-xiang YE, Xu DONG, Chun TANG
• Format: Journal Article
• Language: Chinese
• Published: Science Press 01.06.2021
• Subjects: nuclear magnetic resonance (nmr); phosphorylation; thermosensor; ubiquitin

Ubiquitin (Ub) is a signaling protein in eukaryotic cells, and it functions in the processes of protein degradation and DNA repairing. The published data indicated that the phosphorylation of Ub on Ser65 leads to two stable solution conformations, which can be regulated by pH. In the present project...