Diagnosis and treatment of acute antibody-mediated rejection in renal transplant: the role of C4d and donor-specific antibody identification

• Published in: Einstein (São Paulo, Brazil) Vol. 7; no. 4; pp. 427 - 435
• Main Authors: Lúcio Roberto Requião Moura, Margareth Afonso Torres, Eduardo José Tonato, Érika Ferraz de Arruda, Eric Roger Wroclawski, Maurício Fregonesi Rodrigues da Silva, Denise Maria Avancine Costa Malheiros, Marcelino de Souza Durão, Alvaro Pacheco-Silva
• Format: Journal Article
• Language: English
• Published: Instituto Israelita de Ensino e Pesquisa Albert Einstein 01.12.2009
• Subjects: Graft rejection/diagnosis; Graft rejection/therapy; HLA antigens; Kidney transplantation; Plasmapheresis

Objective: To evaluate the incidence of antibody-mediated rejection after the C4d  and  donor specific antibody  detection was provided by Luminex in renal transplantation biopsies; to compare acute antibody-mediated  rejection characteristics as related to acute cellular rejection; to evaluate the...