Propofol-ketamine and propofol-fentanyl as anesthetic combinations in ambulatory colonoscopy

• Published in: Revista electrónica "Dr. Zoilo E. Marinello Vidaurreta" Vol. 44; no. 5
• Main Authors: Diley Estrada-Ramos, Lisbet Leyva-Pérez, José Luis Barreda-Pavón, David Herlán Sánchez-Pérez, Ana Maryani Gallardo-Pedraza
• Format: Journal Article
• Language: Spanish
• Published: Universidad de Ciencias Médicas de Las Tunas 01.10.2019
• Subjects: ambulatory surgical procedures; anesthetics, combined; colonoscopy; conscious sedation

Background: the best type of sedation/analgesia for gastrointestinal endoscopic procedures is yet to be defined. Among the combinations used are ketamine at subclinical dose with propofol and propofol with fentanyl.Objective: to characterize the use of propofol-ketamine and propofol-fentanyl as inducing agents during ambulatory colonoscopy, in patients treated at the “Dr. Ernesto Guevara de la Serna” Hospital of Las Tunas, between September 2016 and December 2018.Methods: a prospective longitudinal study was carried out with patients undergoing ambulatory colonoscopy, in the aforementioned institution and during the period herein declared. The sample consisted of 300 patients of the 18 to 70 age group with ASA 1 and ASA 2 physical status. They were divided into two groups of 150, one group with anesthetic combination, randomly selected.Results: male patients predominated. The average age was 60.4 years for women and 58.6 years for men; the highest number of cases were classified as ASA 2. With propofol-fentanyl the results were: 40,67 % of patients with bradycardia, 57 % were normotensive, 23 patients (15,33 %) presented less than 94 % of oxygen saturation. With propofol-ketamine the results were: 45,33 % kept a normal heart rate, 65,3 % normotensive, 64 % with complete oxygen saturation and shorter recovery time (at 20 minutes 36 % of the patients recovered). Both anesthetic techniques caused some manifestations such as nausea, vomiting and drowsiness, to a greater extent with propofol-fentanyl.Conclusions: the use of the two anesthetic combinations was characterized in the patients who underwent colonoscopy.