Comparison of Interferon-Gamma Release and Tuberculin Skin Test for Detection of Latent Tuberculosis Infections in Iranian Elderly Patients

• Published in: Majallah-i mīkrub/shināsī-i pizishkī-i Īrān Vol. 11; no. 2; pp. 17 - 25
• Main Authors: Azadeh Mansourzadeh, Sahar Honarmand Jahromi, Majid Khoshmirsafa, Reza Falak
• Format: Journal Article
• Language: English
• Published: Farname 01.06.2017
• Subjects: Latent tuberculosis; Quantiferon; Tuberculin skin test

Background and Aims: Tuberculin skin test is a common method for diagnosis of latent tuberculosis but it has a high rate of false positivity and false negativity. In Quantiferon test, the interferon gamma secreted by lymphocytes in response to Mycobacterium tuberculosis antigens is measured. This st...