EXPRESSION CHARACTERISTICS OF MARKERS OF PROLIFERATIVE ACTIVITY, APOPTOSIS AND CELL DIFFERENTIATION IN PATIENTS WITH PREMALIGNANT LESIONS AND CANCER OF THE LARYNX

• Published in: Sibirskiĭ onkologicheskiĭ zhurnal Vol. 1; no. 5; pp. 74 - 79
• Main Authors: О. V. Cheremisina, O. V. Pankova, К. Yu. Menshikov, E. L. Choinzonov
• Format: Journal Article
• Language: Russian
• Published: Russian Academy of Sciences, Tomsk National Research Medical Center 01.02.2016
• Subjects: premalignant lesions, laryngeal cancer, diagnostic markers, markers of apoptosis, cell differentiation and proliferative activity

The purpose of the study was to determine the informative value of р53, CD 138 and Кi 67 markers in mucosal stratified squamous epithelium of patients with precancerous laryngeal lesions and laryngeal cancer. Material and methods. Expression of the above markers was analyzed in 80 patients with chro...