Flavivirus Infection of italic toggle="yes">Ixodes scapularis /italic> (Black-Legged Tick) italic toggle="yes">Ex Vivo /italic> Organotypic Cultures and Applications for Disease Control

• Published in: mBio Vol. 8; no. 4
• Main Authors: Jeffrey M. Grabowski, Konstantin A. Tsetsarkin, Dan Long, Dana P. Scott, Rebecca Rosenke, Tom G. Schwan, Luwanika Mlera, Danielle K. Offerdahl, Alexander G. Pletnev, Marshall E. Bloom
• Format: Journal Article
• Language: English
• Published: American Society for Microbiology 01.09.2017
• Subjects: dsRNA; Langat virus; metabolism; midgut; Powassan virus; RNA interference

ABSTRACT Ixodes scapularis ticks transmit many infectious agents that cause disease, including tick-borne flaviviruses (TBFVs). TBFV infections cause thousands of human encephalitis cases worldwide annually. In the United States, human TBFV infections with Powassan virus (POWV) are increasing and ha...