Microwave-assisted one-pot efficient synthesis of functionalized 2-oxo-2-phenylethylidenes-linked 2-oxo-benzo[1,4]oxazines and 2-oxo-quino[1,4]oxalines: Synthetic Applications, Antioxidant activity, SAR and Cytotoxic Studies

• Published in: Acta chimica Slovenica Vol. 64; no. 4; pp. 988 - 1004
• Main Authors: Vashundhra Sharma, Pradeep K. Jaiswal, Dharmendra K. Yadav, Mukesh Saran, Jaroslav Prikhodko, Manas Mathur, Ajit K. Swami, Irina V. Mashevskaya, Sandeep Chaudhary
• Format: Journal Article
• Language: English
• Published: Slovenian Chemical Society 01.12.2017
• Subjects: 2-oxo-benzo[1,4] oxazines; 2-oxo-quino[1,4]oxalines; Antioxidant; Benzo[1,4]oxazines; DPPH; FRAP; Microwave-Assisted Organic Synthesis (MAOS)

A microwave-assisted, environmentally benign green protocol for the synthesis of functionalized (Z)-3-(2-oxo-2-phenylethylidene)-3, 4-dihydro-2H-benzo[b][1,4]oxazin-2-ones 11a-n in excellent yields (upto 97%) and (Z)-3-(2-oxo-2-phenylethylidene)-3,4-dihydroquinoxalin-2(1H)-ones 14a-h (upto 96% yield...