Stevens-Johnson syndrome and toxic epidermal necrolysis: case series and brief literature review

Stevens-Johnson syndrome (SJS) and toxic epi- dermal necrolysis (TEN) are rare forms of delayed-type drug hypersensitivity reactions (DHRs) with extensive skin necrosis and exfoliation. Drugs are the main cause of SJS and TEN in both adults and children. The most common medications are allopurinol,...

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Published inArmenian Journal of Health & Medical Sciences pp. 67 - 72
Main Authors Aloyan, Tatevik, Kalikyan, Zaruhi, Harutyunyan, Sona, Zakaryan, Alexandra, Movsisyan, Mariam, Ktsoyan, Lusntag, Karslyan, Ovanes, Hakobyan, Armine
Format Journal Article
LanguageEnglish
Published 30.11.2023
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Summary:Stevens-Johnson syndrome (SJS) and toxic epi- dermal necrolysis (TEN) are rare forms of delayed-type drug hypersensitivity reactions (DHRs) with extensive skin necrosis and exfoliation. Drugs are the main cause of SJS and TEN in both adults and children. The most common medications are allopurinol, aromatic antiepileptics and sulfonamides with seasonal, geographical and ethnic variations. The purpose of this paper is to present the cases of SJS/TEN which were successfully treated during the year of 2021 in our department and to provide a brief literature review.
ISSN:2738-2737
2738-2737
DOI:10.54235/27382737-2023.v3.1-67