Host-directed therapy in foals reduces the severity of clinical pneumonia against Rhodococcus equi intrabronchial challenge

• Published in: The Journal of immunology (1950) Vol. 204; no. 1_Supplement; pp. 92 - 92.11
• Main Authors: Bordin, Angela Ilha, Giguere, Steeve, Bray, Jocelyne, Berghaus, Londa, Hook, Magnus, Scott, Brenton, Johnson, Rena, Cohen, Noah
• Format: Journal Article
• Language: English
• Published: 01.05.2020

Pneumonia caused by Rhodococcus equi, an intracellular bacterium that infects macrophages, is an important cause of disease and death in immunocompromised hosts, especially foals. No vaccine is available, and control is based on antibiotic treatment of subclinical cases, increasing the pressure for...