Metabolomic analysis of macrophage activation and relevance of the cross-talk between energetic metabolism and polarized gene expression (172.12)

• Published in: The Journal of immunology (1950) Vol. 188; no. 1_Supplement; pp. 172 - 172.12
• Main Authors: Bosca, Lisardo, Través, Paqui, Pimentel-Santillana, María, de Atauri, Pedro, Marin, Silvia, Cascante, Marta
• Format: Journal Article
• Language: English
• Published: 01.05.2012

Abstract Immune activation rapidly and substantially enhances metabolic outputs. Macrophage activation is followed by rapid changes in nutrient flux, which also seems to be necessary for immune activation, indicating that signals produced by immune cells might directly regulate their metabolism. Mac...