Abstract 371: Chromatin Remodeling Mechanisms by Bromodomain PHD Finger Transcription Factor in Cardiac Hypertrophy and Heart Failure

• Published in: Circulation research Vol. 125; no. Suppl_1
• Main Authors: Awad, Salma M, Zahid, Esra, Al-Shalan, Sarah, Alaiya, Ayodele, Al-Tinawi, Qamar, Al-Sheikh, Amar, Kunhi, Muhammed, Al-Haffar, Kamar, Al-Buraiki, Jehad, Eyjolsson, Atli, Al-Habib, Waleed, Poizat, Coralie I
• Format: Journal Article
• Language: English
• Published: 02.08.2019

Abstract only Alteration of chromatin conformation has a profound effect on gene expression, and can lead to heart failure, which remains a major cause of death worldwide. ATP-dependent chromatin remodelers utilize the energy of ATP to remodel chromatin in specific regions of the genome. However, th...