Abstract 346: Tuberin S1365 Phosphorylation Regulates Mechanistic Target of Rapamycin Complex 1 (mTORC1) Pathological Signaling While Sustaining Metabolic Sensor Function

Abstract only Rationale: The Mechanistic Target of Rapamycin complex 1 (mTORC1) integrates signaling and sensory inputs to maintain cardiomyocyte homeostasis, and itself is negatively regulated by the signaling nexus tuberin (TSC2). We identified a novel TSC2 phosphorylation site S1365 (pS1365) targ...

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Bibliographic Details
Published inCirculation research Vol. 125; no. Suppl_1
Main Authors Dunkerly-Eyring, Brittany L, Vera, Miguel P, Oeing, Christian U, Ranek, Mark J, Kass, David A
Format Journal Article
LanguageEnglish
Published 02.08.2019
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ISSN0009-7330
1524-4571
DOI10.1161/res.125.suppl_1.346

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