Abstract 8912: Pinch Proteins Are Essential for Cardiac Protein Kinase B Signaling

• Published in: Circulation (New York, N.Y.) Vol. 124; no. suppl_21
• Main Authors: Frese, Karen S, Meder, Benjamin, Sedaghat-Hamedani, Farbod, Huttner, Inken G, Katus, Hugo A, Rottbauer, Wolfgang
• Format: Journal Article
• Language: English
• Published: 22.11.2011

Abstract only Integrin-linked kinase (ILK) is essential for cell maturation, migration and proper adhesion of the cardiac intercalated disks and costameres. It furthermore is as an essential component of the cardiac mechanical stretch sensor. Until now, the precise molecular function of ILK and its...