Abstract 51: A Critical Role for Outside-In Signaling of Integrin AlphalIIIb/Beta3 in Shear-Dependent Platelet Microvesicle Formation and Phosphatidylerine Exposure

• Published in: Arteriosclerosis, thrombosis, and vascular biology Vol. 37; no. suppl_1
• Main Authors: Pang, Aiming, Cui, Yujie, Delaney, Michael K, Stojanovic-Terpo, Aleksandra, Du, Xiaoping
• Format: Journal Article
• Language: English
• Published: 01.05.2017

Abstract only Platelets promote coagulation mainly by exposing membrane phosphatidylserine (PS) and releasing PS-expressing microvesicles (MV). We have recently shown that PS exposure and MV release induced by platelet agonists requires shear stress. To identify the receptor responsible for the shea...