Abstract AP18: PRO-INVASIVE TUMOUR-STROMA INTERACTIONS: ROLE OF THE SECRETED OXIDOREDUCTASE CLIC3

• Published in: Clinical cancer research Vol. 25; no. 22_Supplement; p. AP18
• Main Authors: Hernandez-Fernaud, Juan R, Ruengeler, Elena, Neilson, Lisa J, Ismail, Shehab, McNeish, Iain, Atkinson, Samuel, Lilla, Sergio, Santi, Alice, Valenzuela, Stella M, Blyth, Karen, Yin, Huabing, Mazzone, Massimiliano, Norman, Jim C, Zanivan, Sara
• Format: Journal Article
• Language: English
• Published: 15.11.2019

Abstract Cancer cells are embedded within a microenvironment populated with cancer associated fibroblasts (CAFs) with whom they establish two-way communications through paracrine factors and physical interactions. Through these interactions, CAFs play pivotal roles in cancer and have emerged as prom...