Abstract A13: Interleukin-1β promotes brain metastasis of breast cancer by activating Notch signaling through reactive astrocytes

• Published in: Cancer research (Chicago, Ill.) Vol. 73; no. 3_Supplement; p. A13
• Main Authors: Xing, Fei, Kobayashi, Aya, Okuda, Hiroshi, Watabe, Misako, Pandey, Puspa R., Pai, Sudha K., Liu, Yin, Wu, Kerui, Watabe, Kounosuke
• Format: Journal Article
• Language: English
• Published: 01.02.2013

Abstract Metastatic diseases are responsible for the majority of the deaths in breast cancer patients, and brain is one of the most common metastatic sites. The metastatic tumor in the brain profoundly affects the cognitive and sensory functions as well as morbidity of patients, and the one year sur...