Abstract PD3-15: Novel cFlip inhibitor suppresses chemotherapy-induced breast cancer stem cell activity through blocking HIF1-α

• Published in: Cancer research (Chicago, Ill.) Vol. 78; no. 4_Supplement; p. PD3-15
• Main Authors: Robinson, T, Turnham, D, Gruca, A, Piggott, L, Clarkson, R
• Format: Journal Article
• Language: English
• Published: 15.02.2018

Abstract Background: The emergence of the cancer stem cell (CSC) hypothesis has helped to explain previously poorly understood clinical concepts such as metastases, late tumour recurrence and resistance to chemotherapy. Triple Negative Breast Cancer (TNBC) has the worst prognosis of all types of bre...