Abstract 3898: Integrating structural variants and single nucleotide variants to uncover evolutionary trajectories in melanoma

Melanoma, a highly heterogeneous cancer, evolves through a complex interplay of genetic alterations, including both single nucleotide variants (SNVs) and structural variants (SVs). To study the evolutionary trajectory of melanoma, we established a model system composed of 24 single-cell-derived clon...

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Bibliographic Details
Published inCancer research (Chicago, Ill.) Vol. 85; no. 8_Supplement_1; p. 3898
Main Authors Cui, Xiwen, Keskus, Ayse G., Malikic, Salem, Liu, Yuelin, Goretsky, Anton, Day, Chi-Ping, Mehrabadi, Farid R., Kolmogorov, Mikhail, Merlino, Glenn, Sahinalp, S. Cenk
Format Journal Article
LanguageEnglish
Published 21.04.2025
Online AccessGet full text
ISSN0008-5472
1538-7445
DOI10.1158/1538-7445.AM2025-3898

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