Abstract 2704: cGAS-STING drives myeloid inflammation in chromosomally unstable esophageal cancer

Esophageal adenocarcinoma (EAC) is an aggressive disease characterized by chromosomal instability (CIN), whereby cells continuously acquire chromosomal abnormalities that promote therapeutic resistance, immune evasion and metastasis. CIN in cancers also fuels the misplacement of genomic DNA in the f...

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Bibliographic Details
Published inCancer research (Chicago, Ill.) Vol. 84; no. 6_Supplement; p. 2704
Main Authors Beernaert, Bruno, Erdal, Erkin, Clark, Rose, Liu, Tong, Hammond, Ester M., Parkes, Eileen E.
Format Journal Article
LanguageEnglish
Published 22.03.2024
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