Abstract 698: Developing a self-targeted cancer immunotherapy using engineered whole tumor cell-based vaccine

• Published in: Cancer research (Chicago, Ill.) Vol. 83; no. 7_Supplement; p. 698
• Main Authors: Chen, Kok-Siong, Mendonca, Natalia Claire, Borges, Paulo, Shah, Khalid
• Format: Journal Article
• Language: English
• Published: 04.04.2023

The administration of inactivated tumor cell lysate is known to induce a potent antitumor immune response, however, their therapeutic efficacy as shown in Phase I-III clinical trials is limited. This could be attributed to the lack of direct cytotoxic effect on tumor cells and the inability to trigg...