Abstract 5831: CD200R signaling contributes to unfavorable tumor microenvironment through regulating production of chemokines by tumor associated macrophages

• Published in: Cancer research (Chicago, Ill.) Vol. 83; no. 7_Supplement; p. 5831
• Main Authors: Lin, Cho-Hao, Talebian, Fatemeh, Li, Yang, Zhu, Jianmin, Zhao, Bolin, Liu, Jin-Qing, Basu, Sujit, Pan, Xueling, Chen, Xi, Yan, Pearlly, Carson, William E., Xin, Gang, Wen, Haitao, Wang, Ruoning, Li, Zihai, Ma, Qin, Bai, Xue-Feng
• Format: Journal Article
• Language: English
• Published: 04.04.2023

Abstract CD200 is overexpressed in human solid tumors such as neuroblastoma and melanoma and is considered as an immune checkpoint molecule for dampening cancer immunity. However, how CD200 affects tumor microenvironment (TME) and host immunity is incompletely understood. In the present study, we ev...