Abstract 42: In vivo subcutaneous and orthotopic cancer xenograft modeling in the SRG immunodeficient rat

• Published in: Cancer research (Chicago, Ill.) Vol. 83; no. 7_Supplement; p. 42
• Main Authors: Begemann, Diane, Javidan, Aida, Dunn, Cynthia, Johnston, Nicolas, Walton, R. Grace, Steffey, Valeriya, Corbin, Ian, Fulcher, Niveen, De Oliveira, Cleusa, Xu, Hu, Uzelac, Mila, Deweyert, Andrew, Ronald, John A., Schmid, Susanne, Hebb, Matthew O., Noto, Fallon K.
• Format: Journal Article
• Language: English
• Published: 04.04.2023

Abstract Human cancer xenografts are a vital tool for understanding tumor biology, growth kinetics, and therapeutic efficacy using animal models. Historically, immunodeficient mice have been the standard rodent species for cancer xenograft modeling. However, an immunodeficient rat that supports a wi...