Abstract 3777: MicroRNA-inducible CRISPR/Cas9 for cell type-specific genome regulation in cancer

• Published in: Cancer research (Chicago, Ill.) Vol. 83; no. 7_Supplement; p. 3777
• Main Authors: Oh, Seung Ja, Shin, Cheol-Hee, Lee, Ji Min, Lee, Juyong, Park, Su Chan
• Format: Journal Article
• Language: English
• Published: 04.04.2023

Abstract MicroRNA-dependent mRNA decay plays an important role in gene silencing by facilitating posttranscriptional and translational repression. Inspired by this intrinsic nature of microRNA-mediated mRNA cleavage, here, we describe a microRNA-targeting mRNA as a switch platform called mRNA bridge...