Abstract 1588: Using glyco-engineered cells with flexible expression of tumor-associated carbohydrates for the generation of highly tumor-specific antibodies

• Published in: Cancer research (Chicago, Ill.) Vol. 83; no. 7_Supplement; p. 1588
• Main Authors: Kehler, Patrik, Kast, Naomi, Weiske, Manon, Gurka, Stephanie, Lischke, Timo, Gellert, Johanna, Danielczyk, Antje
• Format: Journal Article
• Language: English
• Published: 04.04.2023

Abstract Introduction: Highly potent therapeutic approaches require clean targets. However, the majority of antibodies in clinical development or approved for cancer therapy address protein targets that are only over-expressed in cancer and yet often show significant expression in healthy organs. Be...